Although the effect of exposure to ambient and household PM 2♵ pollution on diabetes has been estimated in different locations and population groups, the current global disease burden attributable to PM 2♵, its temporal trends, and its magnitude relative to other known diabetes risk factors have not yet been evaluated. The well documented increase in incidence and mortality from inflammation has been highlighted as a relevant biological mechanism linking air pollution exposure to diabetes. Behavioural and metabolic risk factors are widely acknowledged to increase diabetes incidence, but epidemiological and experimental evidence also supports a relationship between long-term exposure to fine particulate matter (PM 2♵) air pollution and increased diabetes incidence and mortality. Type 2 diabetes is a major global health concern, contributing to approximately 1♵ million deaths, 31 million years of life lost, and 35 million years lived with disability in 2019. The Lancet Regional Health – Western Pacific.The Lancet Regional Health – Southeast Asia.The Lancet Gastroenterology & Hepatology.
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